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Egyptian Journal of Forensic Sciences
Fig. 5 | Egyptian Journal of Forensic Sciences

Fig. 5

From: Cytotoxicity associated with acute and chronic administration of synthetic cannabinoids “Strox” in the brain, liver, heart, and testes of male albino rats: histological and immunohistochemical study

Fig. 5

Photomicrographs of sections in the cerebellar cortex immunohistochemically stained with caspase-3 (×400). A and B Negative and positive control groups show negative caspase-3 immunoreaction in cytoplasm and nuclei of cells in granular, molecular, and Purkinje cell layers. C Acute treated group shows few positive reactions in cells of granular (thick arrow), molecular (arrowhead), and Purkinje cell layers (arrow). D Chronic treated group reveals strong positive reaction in cells of granular (thick arrow), molecular (arrowhead), and Purkinje cell layers (arrow). E Chronic withdrawal group shows weak immunoreactivity in cells of granular (thick arrow) and Purkinje cell layers (arrow) compared to the chronic group

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