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Fig. 5 | Egyptian Journal of Forensic Sciences

Fig. 5

From: Autopsy findings in COVID-19 infection-related death: a systematic review

Fig. 5

Extrapulmonary histological features of 10 fatal cases of coronavirus disease 19 (COVID-19), autopsied by the use of ultrasound-guided minimally invasive autopsy. AC Skin collected with a punch needle, showing a perivascular mononuclear infiltrate at the superficial dermis (A), purpura (B), and fibrinoid alteration in small vessels of the dermis (B) and hypodermis (C). D Thoracic skeletal muscle with myositis and myolisis. EG Spleen showing red pulp haemorrhage and lymphoid hypoplasia (E), splenitis and extramedullary haematopoiesis (F, arrow), and thrombosis and vasculitis in a large artery (G). H A thoracic lymph node with hyperplasia of sinusoidal histocytes, haemophagocytosis, and activated lymphocytes. I Liver with macrovesicular steatosis, coagulative necrosis in the central area, and sinusoidal congestion with fibrin thrombi (arrows). J, K Kidney with fibrin thrombi in the capillary tuft (J, arrows), and a collapsed tuft and interstitial fibrosis (K). L Heart with hypertrophy of cardiomyocytes and extensive myocardial fibrosis (previous infarction). Note: Source of figure from Duarte-Neto et al. (2020

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