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Table 1 Selected methods of forensic age estimation

From: Age estimation using DNA methylation technique in forensics: a systematic review

No Reference Method Source of samples N Age MADa RMSE/SEE
1 Weidner et al. 2014 Telomere length Blood 104 18–84 18.2 23.1b
DNA methylation Blood 151 18–84 5.43 7.2b
2 Zubakov et al. 2016 mRNA methylation* Blood 267 22–84 9.195 11.595c
DNA methylation Blood 216 4–82 5.07 6.97c
Telomere length Blood 305 22–84 12.276 15.362c
sjTRECs Blood 306 18–84 9.757 11.935c
3 Cho et al. 2017 sjTRECs Blood 100 20–74 10.33 10.55c
DNA methylation Blood 100 20–74 4.18 -
  1. N: number of samples; Age in years; aMAD: mean absolute deviation (in years); bRMSE: root mean square error (in years); cSEE: standard error of the estimate (in years); sjTRECs: signal-joint T-cell receptor excision circles; *Genes: NRCAM, ABLIM1, LRRN3, NELL2, SLC16A10, NOG, AK5, CCR7, CFH, housekeeping genes: ACTB, GAPDH