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Table 4: Grading of the histopathological changes in liver sections of four studied groups

From: Therapeutic effects of N-acetylcysteine against malathion-induced hepatotoxicity

Histopathology findings Group 1 Group 2 Group 3 Group 4
Cellular changes Cytoplasmic clearing +++ +
Nuclear hyperchromasia +++ ++
Nucleomegaly ++
Inflammation (focal necrosis) +++ +
Portal fibrosis +++ +
Interstitial hemorrhage +++
Portal vein congestion +++ +
Sinusoidal obliteration +
  1. None (–), mild (+), moderate (++) and severe (+++).