Table 4: Grading of the histopathological changes in liver sections of four studied groups
From: Therapeutic effects of N-acetylcysteine against malathion-induced hepatotoxicity
Histopathology findings | Group 1 | Group 2 | Group 3 | Group 4 | |
|---|---|---|---|---|---|
Cellular changes | Cytoplasmic clearing | – | – | +++ | + |
Nuclear hyperchromasia | – | – | +++ | ++ | |
Nucleomegaly | – | – | ++ | – | |
Inflammation (focal necrosis) | – | – | +++ | + | |
Portal fibrosis | – | – | +++ | + | |
Interstitial hemorrhage | – | – | +++ | – | |
Portal vein congestion | – | – | +++ | + | |
Sinusoidal obliteration | – | – | + | – | |