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Table 3 Comparison between on immune-modulatory markers, inflammatory markers and AChE activity within the four studied groups

From: Therapeutic effects of N-acetylcysteine against malathion-induced hepatotoxicity

Measured parameters Group 1 Group 2 Group 3 Group 4
leukocyte count (cells/mm3) 4.1 ± 0.38 4.12 ± 0.47 11.73 ± 2.6ab 6.81 ± 1.67abc
MPO (U/gm) 2.49 ± 0.38 2.79 ± 0.47 11.7 ± 5.97ab 5.32 ± 2.37abc
CD4 % 32.41 ± 2.52 32.26 ± 4.23 57.18 ± 9.86ab 44.1 ± 6.28abc
CD8 % 25.52 ± 2.98 28.16 ± 3.97 58.92 ± 11.69ab 35.03 ± 8.88abc
IL-1b 1 ± 0.03 1.01 ± 0.02 6.80 ± 2.26ab 2.95 ± 1abc
IL-6 1.17 ± 0.6 1.04 ± 0.05 5.72 ± 1.92ab 2.71 ± 1.0abc
IFN-γ 1.04 ± 0.06 1.04 ± 0.05 9.24 ± 2.82ab 3.48 ± 1.08abc
AChE (μ/mg protein) 23.9 ± 3.48 30.08 ± 5.37a 12.37 ± 3.69ab 21.91 ± 5bc
  1. Values are represented in mean ± standard deviation (S.D)
  2. Group 1: control (negative), group 2: NAC only, group 3: malathion only, group 4: malathion plus NAC
  3. aSsignificant compared to corresponding value in group 1 at P < 0.05
  4. bSignificant compared to corresponding value in group 2 at P < 0.05
  5. cSignificant compared to corresponding value in group 3 at P < 0.05