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Table 3 Mean levels of the measured biochemical parameters among the studied groups

From: Blood biomarkers of nicotine-induced toxicity in healthy males

Variable

Non-smokers (n = 20)

Passive smokers (n = 30)

Active smokers (n = 40)

Total (n = 90)

p value

8-OHdG (ng/ml) (mean ± SD)

0.77 ± 0.39

0.84 ± 1.18

3.59 ± 1.98

2.04 ± 2.03

< 0.001**

Cotinine (ng/ml) (mean ± SD)

1.47 ± 1.06

1.67 ± 1.77

13.9 ± 5.26

7.06 ± 7.16

< 0.001**

MDA (nmol/ml) (mean ± SD)

28.24 ± 24.82

24.33 ± 20.09

96.69 ± 25.22

57.36 ± 42.37

< 0.001**

SOD (U/ml) (mean ± SD)

1.79 ± 0.65

1.88 ± 0.63

0.62 ± 0.28

1.3 ± 0.79

< 0.001**

TAC (U/ml) (mean ± SD)

18.99 ± 5.47

18.41 ± 5.97

7.41 ± 2.2

13.65 ± 7.19

<0.001**

  1. **Highly significant p < 0.001
  2. 8-OHdG 8-hydroxy-2′-deoxyguanosine; MDA malondialdehyde; SOD superoxide dismutase; TAC total antioxidant capacity