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Table 2 Changes in serum levels of LH, FSH, testosterone, and acetylcholinesterase of mice after 4 weeks of exposure to curcumin (200 mg/kg/day), malathion (27 mg/kg bw), and their combination. n = 12 mice for each group

From: Malathion induced testicular toxicity and oxidative damage in male mice: the protective effect of curcumin

Parameters

G1 (control)

G2 (curcumin)

G3 (malathion)

G4 (malathion + curcumin)

LH (mIU/mL)

2.85 ± 0.05

2.90 ± 0.08

1.38 ± 0.07ab

2.71 ± 0.07c

FSH (mIU/mL)

2.76 ± 0.05

2.78 ± 0.04

5.31 ± 0.31ab

2.89 ± 0.05c

TS (ng/ml)

2.90 ± 0.11

2.98 ± 0.15

1.87 ± 0.10ab

2.80 ± 0.09c

Ache (μmol SH/g/min)

7.03 ± 0.16

7.02 ± 0.23

4.78 ± 0.15ab

6.87 ± 0.12c

  1. Data are mean ± SD
  2. G1 control, G2 curcumin, G3 malathion, G4 malathion + curcumin, LH luteinizing hormone, FSH follicle-stimulating hormone, TS testosterone, Ache acetylcholinesterase
  3. aCompared to the control (G1) group—significant at p < 0.05
  4. bCompared to curcumin (G2) group—significant at p < 0.05
  5. cCompared to malathion (G3) group—significant at p < 0.05