Table 2 Forensic exhibits and some epigenetic markers (CpG) information available using Illumina Infinium HumanMethylation450 BeadChip array
From: Crime investigation through DNA methylation analysis: methods and applications in forensics
S. No. | Forensic exhibits | Gene | Map Infoc | CpG Target/Illumina IDc | References |
|---|---|---|---|---|---|
1. | Blood/MNCa | MAFG SBNO2 MYO1G NCOR2 | Chr17: 79881543 Chr19: 1155225 Chr7: 45018849 Chr12: 124950720 | cg01543184 cg06578434 cg10673833 cg25922751 | (Thompson et al., 2012; Smith et al., 2014; Benton et al., 2015; Lee et al., 2015) |
Saliva/BECb | DMRTA2 BARX1 HOXA3 NFIX | Chr1: 50884480 Chr9: 96715256 Chr7: 27146262 Chr19: 13112283 | cg10512745 cg13398482 cg01964852 cg22824635 | ||
Vaginal Secretion/Menstrual Fluid | HOXD9 HOTAIR C3 SHANK3 | Chr2: 176988203 Chr12: 54355528 Chr19: 6721955 Chr22: 51169500 | cg22541735 cg26079753 cg14279361 cg06422471 | ||
Semen | ACCN4;ASIC4 PLEC;MIR661 SARS ANKAR DACT1 USP49 | Chr2: 220379058 Chr8: 145018185 Chr1: 109756023 Chr2: 190540650 Chr14: 59104243 Chr6: 41862737 | cg24743778 cg26763284 cg18346935 cg05540789 cg04216397 cg01289140 | ||
2. | Monozygotic twins | SLC6A4/SERT MAOA PTPN7 | Chr17: 28562220 ChrX: 43515457 Chr1: 202129566 | cg22584138 cg14191108 cg18384097 | |
3. | Age | CELF6 NHLRC1 EDARADD ASPA PDE4C ELOVL2 | Chr15: 72612125 Chr6: 18122719 Chr1: 236559675 Chr17:3377265 Chr19: 18343901 Chr6: 11043368 | cg21801378 cg22736354 cg09809672 cg02228185 cg17861230 cg01799681 | (Bocklandt et al., 2011; Zykovich et al., 2013; Bekaert et al., 2015; Jones et al., 2015; Eipel et al., 2016) |
4. | Race/Ethnic | CD101; IGSF2 PLSCR2 KRTCAP3 PM20D1 | Chr1:117544416 Chr3:146213845 Chr 2: 27665128 Chr1:205818956 | cg23953831 cg15847988 cg24768116 cg17178900 | (Fraser et al., 2012; Heyn et al., 2013) |
5. | Smoking Obesity T2D Pain | AHRR F2RL3 PLIN4 FTO ADCY1 | Chr5: 373378 Chr19: 17000585 Chr19: 4517804 Chr16: 53809231 Chr11: 507970 | cg05575921 cg03636183 cg01907005 cg26580413 cg06417962 | (Breitling et al., 2011; Zeilinger et al., 2013; Bell et al., 2014; Benton et al., 2015) |