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Table 2 Comparison of testicular oxidant/antioxidant parameters (MDA, SOD, and GPX) in all studied groups

From: The possible protective effect of the nuclear factor kappa B inhibitor pyrrolidine dithiocarbamate on tramadol-induced testicular damage in rats

Parameters

Groups (n = 10)

Group I

Group II

Group III

Group IV

MDA (nmol/mg protein)

mean ± SD

111.75 ± 5.63

106.07 ± 5.71

197.86 ± 13.3

135.61 ± 6.18

P value of LSD

 

P = 0.138a

P < 0.001*a,b

P < 0.001*a,b,c

SOD (U/mg protein)

mean ± SD

73.68 ± 7.27

75.72 ± 6.21

35.55 ± 5.33

56.5 ± 4.68

P value of LSD

 

P = 0.449a

P < 0.001*a,b

P < 0.001*a,b,c

GPX (U/mg protein)

mean ± SD

23.28 ± 2.14

24.58 ± 2.65

14.22 ± 2.54

19.79 ± 2.05

P value of LSD

 

P = 0.226a

P < 0.001*a,b

P < 0.01 *a, P < 0.001*b,c

  1. MDA, malondialdehyde; SOD, superoxide dismutase; GPX, glutathione peroxidase; SD, standard deviation; n, number of rats in each group; LSD, least significant difference
  2. *Significant result
  3. ap value versus group I
  4. bp value versus group II
  5. cp value versus group III